| Online ISSN | : | 2953-7983 |
| Print ISSN | : | 1829-1767 |
About the Journal
Proceedings of the YSU B: Chemical and Biological Sciences aims to publish original research papers and survey articles in all areas of chemistry and biology. Proc. YSU B: Chem. Biol. Sci. accepts also review articles, short communications, conference proceedings, Ph.D and doctoral thesis’s and other items with a detailed exposition of results, experiments and examples. One of purposes is to reflect the progress of the research in all areas of chemistry and biology in Armenia and, by providing an international forum, to stimulate its further developments.
Current Issue
Biology
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Biology
THE COMBINED EFFECT OF TRIFOLIUM PRATENSE L. (RED CLOVER) AND VIBRATION ON RAT BRAIN PROTEIN AMIDATION DURING AGING
AbstractVibration pathologies are one of the pressing issues in medicine and biochemistry. It is known that under the influence of vibration, the content of amide groups of proteins in tissues increases, which is one of the biochemical indicators of the organism. It has been shown that amidation occurs to a lesser extent in brain proteins of old rats exposed to vibration than in young rats. When Trifolium pratense L. flowers are added to the animals' diet, the level of amidation during vibration in old rats also decreases to a lesser extent than in young rats. However, in both cases, the level of amidation occurring is reduced by half under the influence of the plant. Based on these results, the use of T. pratense plant material is proposed as a means of reducing the negative impact of vibration on the body.
ReferencesBadalyan I.A., Dilbaryan A.S., Davtyan M.A. Amidation of Rat Brain Proteins during Hypoxia. Reports of NAS RA 113 (2013), 391–395 (in Russian).
Simonyan L.P., Papyan K.M., Badalyan I.A. Influence of Vibration on Ammonium Fermentation in the Rat Brain. Materials of the 2nd Republican Youth Scientific Conference (2001), 146–153 (in Russian).
Badalyan I.A., Hayrapetyan N.K., Poladyan A.A. The Effect of the Plant Trifolium pratense L. on Amidation of Brain Proteins in Rats Exposed to Vibration. Proc. of the YSU. Chem. and Biol. Sci. 59 (2025), 36–42. https://doi.org/10.46991/PYSUB.2025.59.1-2.036
Antoshina L.I., Saarkoppel L.M., Pavlovskaya N.A. Influence of Vibration on Biochemical Values Characterizing Oxidative Metabolism, Immunity, Metabolism in Muscular and Connective Tissues. Labor. Med. Industr. Ecol. 2 (2009), 32–37 (in Russian).
Pacurari M., Waugh S., Krajnak K. Acute Vibration Induces Peripheral Nerve Sensitization in a Rat Tail Model: Possible Role of Oxidative Stress and Inflammation. Neuroscience 398 (2019), 263–272. https://doi.org/10.016/j.neuroscience.2018.12.010
Tumanyan L.R., Nikoyan A.A., et al. Arginase Activity of Different Organs in Rats Influenced by Right-sided Labyrinthectomy. Biolog. Journ. Armenia 4 (2013), 35–38 (in Russian).
Karapetyan M.A., Adamyan N.Yu., et al. Influence of Trifolium pratense on Neurophisiological Processes and Amidation of Rat Brain Proteins under Hypoxic Conditions. Mater. of the Conf. "Physiological Mechanisms of Regulation of the Organism's Activity". Yerevan (2012), 180–185 (in Russian).
Badalyan I.A., Trchounian A.A. The Effect of Trifolium pretense Plant (Red Clover) on Lipid Peroxidation Processes in Rat Brain and Liver Exposed to Hypobaric Hypoxia. Biolog. Journ. Armenia 2 (2018), 39–43 (in Russian).
Badalyan I.A., Poladyan A.A. The Effect of Antioxidant Activity of Plants Trifolium pretense L. and Crataegus laevigata on Lipid Peroxidation in Rat’s Tissues Exposed to Hypobaric Hypoxia. Proc. of the YSU. Chem. and Biol. Sci. 56 (2022), 239–244. https://doi.org/10.46991/PYSU:B/2022.56.3.239
Esmaeili K.A., Taha M.R., et al. Antioxidant Activity and Total Phenolic and Flavonoid Content of Various Solvent Extracts from in vivo and in vitro Grown Trifolium pratense L. (Red Clover). BioMed. Res. Intern. Article ID 643285 (2015), 1–11.
Sahakyan N., Petrosyan M., et al. Plant Origin Phenolics as Prospective Antioxidants: State-of-Art for Application. Adv. Biol. Sci. Res. 7 (2019), 266–269. https://doi.org/10.2991/isils-19.2019.65
Vlaisavljević S., Kaurinović B., et al. Profile of Phenolic Compounds in Trifolium pratense L. Extracts at Different Growth Stages and Their Biological Activities. Int. J. Food Properties 20 (2017), 3090–3111. https://doi.org/10.1080/10942912.2016.1273235
Pushkina I.V., Lukash A.I. Easy and Hard Hydrolysable Amide Groups in Protens. Izv. Severo-Kavkaz. Nauch. Tsentra Vyssh. Shk. Yestestven. Nauki 2 (1976), 95–97 (in Russian).
Silakova A.I., Trush G.P., Iaviliakova A. A Micromethod of Ammonia and Glutamine in Tri¬chloroacetic Acid Tissue Extracts. Voprosy Meditsinskoi Khimii 8 (1962), 538–544 (in Russian).
Welham S.J., Gezan S.A., et al. Statistical Methods in Biology: Design and Analysis of Experiments and Regression. CRC Press, Taylor & Francis Group (2015), 592.