INVESTIGATION OF MIXED KINETICS OF LIGANDS ADSORPTION ON DNA

Authors

  • M. A. Elizbaryan Chair of Biophysics, YSU, Armenia

DOI:

https://doi.org/10.46991/PYSU:B/2010.44.1.034

Keywords:

duplexes of DNA, mathematical model, variants of adsorption, adsorption and desorption rates

Abstract

In this work the mathematical model of kinetics of ligands adsorption on duplexes of DNA with the account of diffusion as well as kinetic stages is constructed. The case when the volume solution directly adjoins to immobilized molecules of DNA is considered. The numerical analysis of nonlinear equations system describing the process of adsorption shows that various variants of adsorption can be realized in a solution depending on a parity between constants of ligands adsorption and desorption rates on DNA, as well as ligands rate diffusion.

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Published

2010-02-24

How to Cite

Elizbaryan, M. A. 2010. “INVESTIGATION OF MIXED KINETICS OF LIGANDS ADSORPTION ON DNA”. Proceedings of the YSU B: Chemical and Biological Sciences 44 (1 (221):34-37. https://doi.org/10.46991/PYSU:B/2010.44.1.034.

Issue

Section

Biology