ADSORPTION OF SHORT LIGANDS ON DNA WITH MODIFICATION OF ADSORPTION CENTER STRUCTURE

V.B. Arakelyan; S.V. Harutyunyan; V.K. Andriasyan

doi:10.46991/PYSU:A/2013.47.2.050

ADSORPTION OF SHORT LIGANDS ON DNA WITH MODIFICATION OF ADSORPTION CENTER STRUCTURE

Authors

V.B. Arakelyan Chair of Molecular Physics, YSU, Armenia
S.V. Harutyunyan Department of Medical Physics, YSMU, Armenia
V.K. Andriasyan Institute of Evolutionary Biology and Environmental Studies, University of Zurich, Switzerland

DOI:

https://doi.org/10.46991/PYSU:A/2013.47.2.050

Keywords:

adsorbing center, bifurcation, potential well, bistable adsorption regime

Abstract

The reversible adsorption of short ligands on DNA at arbitrary filling has been theoretically investigated, the kinetics of adsorption of ligands on DNA being described in a self-consistent way with the modified structure of an adsorbing center. The case when one adsorbed ligand occupied two adsorption centers on DNA was considered. It was shown that an allowance for the modification of the potential well of the adsorbing center led to the possibility of realizing various regimes of adsorption.

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Published

2013-06-20

How to Cite

Arakelyan, V., Harutyunyan, S., & Andriasyan, V. (2013). ADSORPTION OF SHORT LIGANDS ON DNA WITH MODIFICATION OF ADSORPTION CENTER STRUCTURE. Proceedings of the YSU A: Physical and Mathematical Sciences, 47(2 (231), 50–57. https://doi.org/10.46991/PYSU:A/2013.47.2.050