Vol. 36 No. 3 (199) (2002)

Literature data concerning empirical and semiempirical correlation equations and parameters obtained by kinetic, spectroscopic (UV, IR, NMR) and thermodynamic methods, which characterize the solvent and which are being used to discuss different reaction series have been analysed. Correlations between considered parameters have been established.

In the present communication the application of multiparametric correlation equations to analyse radical and nonradical reactions has been discussed. It has been shown that parameters characterizing the solvents may be used to examine the action of specific as well as nonspecific solvation’s effect, but also to classify the solvents.

The kinetics of anionic polymerization of acrylonitrile in sulphoxides (DMSO and DESO) solutions in the presence of the nitrates and chlorides of aluminium and zinc and Al(NO₃)₃·6DMSO complex have been investigated. It was maintained that the polymerization has anionic character. The order of reaction by initiators have been defined =0.5. It was ascertained that in first stage of reaction occurring to interaction of salts with sulphoxides, but in case of complex we have preliminary co-ordination of metal ion to sulfoxide. The interaction of water on acrylonitrile polymarization in sulfoxide solutions have been investigated too. It was shown that in case of DESO water is the only inhibitor of anionic polymerization.

Ampicyline interacts with Nile Blue in hydrochloric acid solutions. The formed ion associate could be extracted by the dichlorethane. Maximal extinction is observed at the value of wavelength 640 nm. Optimal acidity of aquans solutions is pH 1.0 by HCl. The optimal quantities of dye is 1.0–1.8 mL of 0.1% solutions. The coefficient of extraction is 88.5%.

Thermographic, crystallooptic and roentgeno-phase investigation of Rb₃AlF₆–K₃YF₆ system has been carried out. It has been shown thet the melting diagram of this system presents itself a continous row of solid solutions with minimum at 896°C and 75 mol % Rb₃AlF₆ content.

New water-soluble derivatives of paraaminobenzenesulfacetamide have been synthesized by means of interaction of sodium derivatives of paraaminobenzene-sulfacetamide with ethylenchlorhydrine, epichlorhydrine, benzyl chloride ethyl ester of monochloracetic acid, N-P-chlorethylmorpholine, alkyl chlorides, phenylhydrazine and thiosemicarbazide. Reactions were carried out in absolute alcohol or dimethylformamide at 90–95°C and equi-molar ratio of reagents.

Microwaves in the frequency range of 30–300 GHz are called millimetre waves (MMWs) because the wavelength in vacuum belongs to the interval of 1–10 mm. There is a substantial number of studies showing biological effects of MMWs at nonthermal intensities, but there is not yet explanation of the interaction phenomena of Extremely High-Frequency Electromagnetic Fields with alive objects, which is very important for diagnosis and therapy.

The investigation of the influence of pH on the fluorescence spectra of bovine liver arginase in solutions has shown that in the region of pH 6.5–9.8, where the enzyme keeps the activity, small conformational changes take place. At the extremal pH values (2.8 and 10.5) and in the presence of high concentrations of urea the intensivity of fluorescence decreases and maximum spectra are shifted. The data suggested that polypeptide chain of arginase is damaged in 8 M urea solutions without any cleavage of disulfide bonds.

The investigation of the influence of pH on the fluorescence spectra of bovine liver arginase in solutions has shown that in the region of pH 6.5–9.8, where the enzyme keeps the activity, small conformational changes take place. At the extremal pH values (2.8 and 10.5) and in the presence of high concentrations of urea the intensivity of fluorescence decreases and maximum spectra are shifted. The data suggested that polypeptide chain of arginase is damaged in 8A/ urea solutions without any cleavage of disulfide bonds.

During two years (2000–2001) the genotoxicity of components of water samples in river Hrazdan (on the territory of Yerevan) using test of somatic mutations in Tradescantia stamen hairs (clone 02) was investigated. The 6 points for the collection of water samples were selected to determine the genotoxicity. The results of the observations witness the changes of mutagenic activity frequencies in samples depending on degree of contamination of river water with different waster during different months and years. Water samples from point 4 (“Hrazdan” stadium) and point 6 (Yerevan Lake) are the more contaminated samples, leading to elevation of the frequency of recessive mutation events. The results witness that it is reasonable to use the Tradescantia 02 clone for the investigation of water contamination on the territory of Yerevan.

In acute experiments on intact spinal rats with beforehand chronical venom intoxication and cool-hardening the influence of armenian adder (Vipera raddei) venom on the basic and evoked (stimulation of n. ischiadicus) electrical activity of single intemeurones of lumbo-sacral area (U-VI lamines at Rexed) of spinal cord was investigated. The statistical analyses on-line was done. At rats with chronical intoxication and cool-hardening only pronounced simplification of activity in the beginning was revealed.

The work shows that after a partial hepatectomy the relative volume of T zone increases in the spleen of rats and domestic hens, which leads to the increase of lymphocytes proliferation intensity in the given region. The quantity of plasmatic cells, on the contrary, decreases.

It have been studied the influence of new form of insectine (titr 60 mid spor/g) on phosphotase activity of forest chestnut and carbonate soils. It has been shown that low insectine treatment doesn’t influence while high treatment even increases the phosphatas activity of investigated soils.

It has been shown that the rate of reaction in case of α-alkyl-α-bromacetic acid is 1.45–1.5 times higher, than for α-alkyl-α-chloroacetic acids. The influence of a-alkyl substitute on the rate of formation of goaled product has been studied.

The intensity of termoshock proteins biosynthesis in yeasts Candida rugosa BCB-925 was investigated. It has been shown that under high temperature (44°C) the synthesis of comparatively low-molecular proteins (M<78 kDa) is 2–3 times more intensive than of high-molecular proteins.

Here is shown correlative relation between mast cells quantity and scar maturation pace at the resection zone of rats and domestic hens liver during two months after partial hepatectomy.