SOME LAMIACEAE FAMILY PLANT ESSENTIAL OIL CHEMICAL COMPOSITION AND THEIR POTENTIAL AS ANTIMICROBIAL AGENTS AGAINST ANTIBIOTIC-RESISTANT BACTERIA

Authors

  • N.Zh. Sahakyan Chair of Biochemistry, Microbiology and Biotechnology, YSU, Armenia
  • M.T. Petrosyan Chair of Biochemistry, Microbiology and Biotechnology, YSU, Armenia
  • A.H. Trchounian Chair of Biochemistry, Microbiology and Biotechnology, YSU, Armenia

DOI:

https://doi.org/10.46991/PYSU:B/2019.53.1.023

Keywords:

essential oils, antibiotic resistance, antibacterial activity

Abstract

The antimicrobial activity of essential oils (EO) from several plants of Lamiaceae family (Ziziphora clinopodioides Lam., Thymus vulgaris L., Ocimum × citriodorum, O. basilicum var. purpureum, O. basilicum var. thyrsiflora, Origanum vulgare L.), spread in Armenia, was studied using agar diffusion method. As test-organisms the ampicillin-resistant Escherichia coli dp5α-pUC18 and non-resistant E. coli VKPM M-17 were used. Dimethyl sulfoxide was used as the solvent and negative control; gentamicin was applied as the positive control. O. × citriodorum, O. basilicum var. purpureum and T. vulgaris EO expressed the strongest activity against E. coli dpα-pUC18; minimal inhibitory concentrations (MIC) was 6.25 μL·mL–1. MIC of the O. basilicum var. thyrsiflora EO was 12.5 μL·mL–1. Z. clinopodioides and O. vulgare EO MIC was 50 μL·mL–1. Thus, EO from the Lamiaceae family plants could be recommended as antimicrobial agents against antibiotic-resistant bacteria.

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Published

2020-04-15

How to Cite

Sahakyan, N.Zh., M.T. Petrosyan, and A.H. Trchounian. 2020. “SOME LAMIACEAE FAMILY PLANT ESSENTIAL OIL CHEMICAL COMPOSITION AND THEIR POTENTIAL AS ANTIMICROBIAL AGENTS AGAINST ANTIBIOTIC-RESISTANT BACTERIA”. Proceedings of the YSU B: Chemical and Biological Sciences 53 (1 (248):23-28. https://doi.org/10.46991/PYSU:B/2019.53.1.023.

Issue

Section

Biology