SYNTHESIS AND ANTIBACTERIAL ACTIVITY STUDIES OF NEW 2-N-SUBSTITUTED 2,5-DIHYDROFURANS
DOI:
https://doi.org/10.46991/PYSU:B/2019.53.3.156Keywords:
2-imino-2,5-dihydrofurans, benzohydrazide, 2-$N$-substituted 2,5- dihydrofurans, synthesis, antibacterial activityAbstract
New 2-N-substituted 2,5-dihydrofurans were successfully synthesized by the convenient and efficient method, which was based on the reaction of functionalized 2-imino-2,5-dihydrofurans with benzohydrazide in glacial acetic acid. Synthesized compounds exhibited moderate to defined antibacterial activities against Grampositive (Staphylococcus aureus – 209p and 1) and Gram-negative (Shigella Flexneri 6858, Esherichia coli 0–55) bacteria compared to furazolidone.
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Published
2019-12-18
How to Cite
Toakmajyan, G.G., L.V. Karapetyan, R.V. Paronikyan, and H.M. Stepanyan. 2019. “SYNTHESIS AND ANTIBACTERIAL ACTIVITY STUDIES OF NEW 2-N-SUBSTITUTED 2,5-DIHYDROFURANS”. Proceedings of the YSU B: Chemical and Biological Sciences 53 (3 (250):156-60. https://doi.org/10.46991/PYSU:B/2019.53.3.156.
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Chemistry
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