DIASTEREOSELECTFV SYNTHESIS OF NEW Ni(II) COMPLEX OF CHIFF’S BASE OF (S)-2-[N-(N'-BENZYLPROLYL) AMINO] BENZOPHENONE WITH ETHER OF (2S, 4R)-4-BROMGLUTAMIC ACID

Authors

  • E. P. Babayan Chair of of Pharmaceutical Chemistry, YSU, Armenia

DOI:

https://doi.org/10.46991/PYSU:B/2006.40.2.091

Keywords:

Schiffs base, Ni(II) complex, $\alpha$-bromacrylic acid, high diastereoselectivity, X-ray structural method

Abstract

Diastereoselectiv reaction of addition of Ni(II) complex Schiffs base of chiral auxiliary (S)-2-[N-(N'-benzylprolyl)amino]benzophenone and glycine to C=C bond of ether of $\alpha$-bromacrylic acid has been investigated. Reaction proceeds in the alcohol, at presence of [(CH3)2CH]2 NH as catalyst. In this work a complex of ether of (2S, 4R)-4-bromglutamic acid with high diastereoselectivity has been obtained, which has been characterized by physical and chemical methods of analysis. The absolute configuration of the complex has been determined by X-ray structural method of analysis.

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Published

2006-05-30

How to Cite

Babayan, E. P. 2006. “DIASTEREOSELECTFV SYNTHESIS OF NEW Ni(II) COMPLEX OF CHIFF’S BASE OF (S)-2-[N-(N’-BENZYLPROLYL) AMINO] BENZOPHENONE WITH ETHER OF (2S, 4R)-4-BROMGLUTAMIC ACID”. Proceedings of the YSU B: Chemical and Biological Sciences 40 (2 (210):91-96. https://doi.org/10.46991/PYSU:B/2006.40.2.091.

Issue

Vol. 40 No. 2 (210) (2006)

Section

Chemistry

License

Copyright (c) 2006 Proceedings of the YSU

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