EXTRACTION-PHOTOMETRIC DETERMINATION OF NORSULFAZOLE BY MEANS OF METHYLENE BLUE BASIC DYE

Authors

  • S. V. Vardanyan Chair of Inorganic and Analytical Chemistry, YSU, Armenia
  • K. H. Galoyan Chair of Inorganic and Analytical Chemistry, YSU, Armenia
  • H. G. Khachatryan Chair of Inorganic and Analytical Chemistry, YSU, Armenia

DOI:

https://doi.org/10.46991/PYSU:B/2008.42.1.085

Keywords:

norsulfazole (sulfathiazole) sodium salt, methylene blue, formation of ionic associate, elaborated technique

Abstract

Interaction of norsulfazole (sulfathiazole) sodium salt with methylene blue basic dye has been studied. Optimal conditions for formation of ionic associate have been determined. It has been estimated that the ionic associate forming may be extracted by means of single extraction procedure at equal volumes of aqueous and organic phases within 8.5–10.0 pH range. Submitting to the Beer’s law observed within 3.8–40.0 mcg/mL norsulfazole contents, light adsorption molar coefficient value at 650 nm wavelength is 20900·300 (L·mol-1·cm-1). Norsulfazole sodium salt interacts with methylene blue in 1:1 molar ratio. The elaborated technique has been applied for determination of norsulfazole in drug tablets.

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Published

2023-09-13

How to Cite

Vardanyan, S. V., K. H. Galoyan, and H. G. Khachatryan. 2023. “EXTRACTION-PHOTOMETRIC DETERMINATION OF NORSULFAZOLE BY MEANS OF METHYLENE BLUE BASIC DYE”. Proceedings of the YSU B: Chemical and Biological Sciences 42 (1 (215):85-89. https://doi.org/10.46991/PYSU:B/2008.42.1.085.

Issue

Vol. 42 No. 1 (215) (2008)

Section

Chemistry

License

Copyright (c) 2023 Proceedings of the YSU

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