$IN~VITRO$ INVESTIGATION OF NEW WATER-SOLUBLE Ag-PORPHYRIN (AgTOEtPyP)

Authors

  • N. S. Babayan Chair of Genetics and Cytology, YSU, Armenia
  • A. L. Gevorgyan Chair of Genetics and Cytology, YSU, Armenia
  • A. G. Tovmasyan Chair of Genetics and Cytology, YSU, Armenia

DOI:

https://doi.org/10.46991/PYSUB.2008.42.2.150

Keywords:

porphyrines, cell population kinetics, morphological and biochemical techniques, chemotherapeutic agent

Abstract

In this work the effect of porphyrines, AgTOEtPyP, on the cell population kinetics was studied in vitro using morphological and biochemical techniques. The results suggested that AgTOEtPyP action consisted in the simultaneous suppression of the cell growth and activation of the cell death. About 40% of the cells were shown to die via apoptotic pathway. So, the porphyrin studied may be attributed to inducers of both necrotic and apoptotic processes. The results obtained support our previous assertion that AgTOEtPyP may be considered as a potential chemotherapeutic agent.

Downloads

Published

2023-09-22

Issue

Vol. 42 No. 2 (216) (2008)

Section

Short Communications

License

Copyright (c) 2023 Proceedings of the YSU

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

“$IN~VITRO$ INVESTIGATION OF NEW WATER-SOLUBLE Ag-PORPHYRIN (AgTOEtPyP)”. 2023. Proceedings of the YSU B: Chemical and Biological Sciences 42 (2 (216): 150-52. https://doi.org/10.46991/PYSUB.2008.42.2.150.

Most read articles by the same author(s)