QUANTITATIVE ANALYSIS OF RNA AND ACIDIC PROTEINS OF MONOBLASTS AND MONOCYTES INFECTED WITH AFRICAN SWINE FEVER VIRUS

Authors

  • H.S. Zakaryan Institute of Molecular Biology of NAS RA
  • Z.A. Karalyan Institute of Molecular Biology of NAS RA

DOI:

https://doi.org/10.46991/PYSU:B/2013.47.1.047

Keywords:

cytophotometry, infected cell, ASFV, cytopathogenesis, disease, nucleus, nucleolus

Abstract

A single cell cytophotometry was used to analyze the amount of RNA and proteins in porcine cells that are susceptible to African Swine Fever Virus (ASFV). The obtained results show that ASFV infection results in depletion of total RNA in the nucleus of monoblasts and monocytes. The level of nuclear acidic proteins in monoblasts is also less, than in control during all time of infection, whereas in monocytes it is higher, than in uninfected cells at the final stage of infection. These data can be used in further researches to elucidate cytopathogenesis of ASFV infection. 

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Published

2013-03-10

How to Cite

Zakaryan, H.S., and Z.A. Karalyan. 2013. “QUANTITATIVE ANALYSIS OF RNA AND ACIDIC PROTEINS OF MONOBLASTS AND MONOCYTES INFECTED WITH AFRICAN SWINE FEVER VIRUS”. Proceedings of the YSU B: Chemical and Biological Sciences 47 (1 (230):47-49. https://doi.org/10.46991/PYSU:B/2013.47.1.047.

Issue

Section

Biology

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