EFFECT OF DNA GC-CONTENT ON INTERACTION WITH METHYLENE BLUE

Authors

  • L.A. Hambardzumyan Chair of Biophysics, YSU, Armenia

DOI:

https://doi.org/10.46991/PYSUB.2015.49.1.045

Keywords:

DNA, GC-content, methylene blue, binding semi-intercalation mode

Abstract

The melting of methylene blue (MB) complexes of DNA with different GC-content sequences at 0.02 M ionic strength of the solution has been carried out. It was shown that the change of melting interval width of MB complexes with DNA increases depending on GC-content enhancement within DNA sequences. It was revealed that MB is bound to DNA by semi-intercalation mode.

Downloads

Published

2015-04-01

Issue

Vol. 49 No. 1 (236) (2015)

Section

Biology

License

Copyright (c) 2015 Proceedings of the YSU

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

“EFFECT OF DNA GC-CONTENT ON INTERACTION WITH METHYLENE BLUE”. 2015. Proceedings of the YSU B: Chemical and Biological Sciences 49 (1 (236): 45-49. https://doi.org/10.46991/PYSUB.2015.49.1.045.