RISK OF FMF DEVELOPMENT AMONG HETEROZYGOUS PATIENTS IN ARMENIAN POPULATION

Authors

  • H.S. Hayrapetyan Center of Medical Genetics and Primary Health Care, Yerevan State Medical University after Mkhitar Heratsi, Armenia
  • T.F. Sarkisian Center of Medical Genetics and Primary Health Care, Armenia
  • S.A. Atoyan Center of Medical Genetics and Primary Health Care, Yerevan State Medical University after Mkhitar Heratsi, Armenia

DOI:

https://doi.org/10.46991/PYSU:B/2016.50.3.048

Keywords:

familial Mediterranean fever, MEFV gene mutations, pseudodominant inheritance

Abstract

aim of this study is the investigation of one mutation carriers of MEFV gene among Armenian population. We designed and established the genetic register for proper collection of patients’ data including their ethnicity, clinical and laboratory data, as well as family cases. According to the results the frequency of FMF inheritance with only one mutation of MEFV gene among Armenian population is about 17.5% and by autosomal-recessive mode (homozygous or compound-heterozygous) is 82.5%.

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Published

2016-11-21

How to Cite

Hayrapetyan, H.S., T.F. Sarkisian, and S.A. Atoyan. 2016. “RISK OF FMF DEVELOPMENT AMONG HETEROZYGOUS PATIENTS IN ARMENIAN POPULATION”. Proceedings of the YSU B: Chemical and Biological Sciences 50 (3 (241):48-52. https://doi.org/10.46991/PYSU:B/2016.50.3.048.

Issue

Vol. 50 No. 3 (241) (2016)

Section

Biology

License

Copyright (c) 2016 Proceedings of the YSU

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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