PREVALENCE OF CLASS 1 INTEGRONS IN CLINICAL ISOLATES OF NON-TYPHOIDAL $SALMONELLA~ENTERICA$ CIRCULATED IN ARMENIA

Authors

  • Magdalina K. Zakharyan Institute of Molecular biology, NAS RA, Armenia

DOI:

https://doi.org/10.46991/PYSU:B/2021.55.1.058

Keywords:

non-typhoid $Salmonella$, multidrug resistance, $S.$ ser. Typhimurium, $S.$ ser. Enteritidis, class 1 integron

Abstract

A total of 182 non-typhoid Salmonella enterica (NTS) isolates recovered from patients between 1996 and 2014 were included in the current study focused on class 1 integron detection and its association with multidrug resistance (MDR) phenotype. A high prevalence of isolates displaying MDR and penta-resistance (resistance to ampicillin, chloramphenicol, streptomycin, sulfonamide, tetracycline) phenotypes of clinical significance was revealed. Serotype-specific prevalence of antimicrobial resistance as well as class 1 integrons and inserted variable segments was detected in isolates. The results indicated the limitations of current antimicrobial therapy to control infections caused by MDR isolates of NTS, especially belonging to serotype Typhimurium.

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Published

2021-04-28

How to Cite

Zakharyan, Magdalina K. 2021. “PREVALENCE OF CLASS 1 INTEGRONS IN CLINICAL ISOLATES OF NON-TYPHOIDAL $SALMONELLA~ENTERICA$ CIRCULATED IN ARMENIA”. Proceedings of the YSU B: Chemical and Biological Sciences 55 (1 (254):58-66. https://doi.org/10.46991/PYSU:B/2021.55.1.058.

Issue

Vol. 55 No. 1 (254) (2021)

Section

Biology

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Copyright (c) 2021 Proceedings of the YSU

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