DEVELOPMENT OF AN HPLC METHOD FOR SIBUTRAMINE IDENTIFICATION. SEARCH FOR UNDECLARED SIBUTRAMINE IN BIOLOGICALLY ACTIVE ADDITIVES APPETITE SUPPRESSANTS

Authors

  • Ruben E. Israyelyan Scientific and Production Center «Armbiotechnology» NAS RA, Armenia
  • Tatevik H. Sargsyan Chair of Biomedicine, Institute of Pharmacy, YSU, Armenia

DOI:

https://doi.org/10.46991/PYSU:B/2022.56.1.031

Keywords:

sibutramine, HPLC analysis, concentration, validation, BAA

Abstract

In this study an available reversed-phase HPLC method for the identification of sibutramine with UV detection and isocratic elution mode was developed, the evaluation of the method applicability and determination of validation indicators were carried out. It has been shown that the developed method meets the current international requirements. To search for sibutramine, the developed method has been used in some biologically active additives ("Lipocarnit", "Pineapple extract", "Turboslim night" and "Turboslim day").

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Published

2022-03-09

How to Cite

Israyelyan, Ruben E., and Tatevik H. Sargsyan. 2022. “DEVELOPMENT OF AN HPLC METHOD FOR SIBUTRAMINE IDENTIFICATION. SEARCH FOR UNDECLARED SIBUTRAMINE IN BIOLOGICALLY ACTIVE ADDITIVES APPETITE SUPPRESSANTS”. Proceedings of the YSU B: Chemical and Biological Sciences 56 (1 (257):31-40. https://doi.org/10.46991/PYSU:B/2022.56.1.031.

Issue

Vol. 56 No. 1 (257) (2022)

Section

Chemistry

License

Copyright (c) 2022 Proceedings of the YSU

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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