A NEW APPROACH TO THE SYNTHESIS OF 3-N-SUBSTITUTED THIENOPYRIMIDINE-4-ONES ON THE BASE OF ETHYL AMINOTHIOPHENECARBOXILATES

Authors

  • G.S. Melikyan Chair of Organic Chemistry, YSU, Armenia
  • A.A. Hovhannisyan Chair of Organic Chemistry, YSU, Armenia
  • L.A. Aristakesyan Chair of Organic Chemistry, YSU, Armenia

DOI:

https://doi.org/10.46991/PYSUB.2011.45.3.030

Keywords:

3-N-substituted thieno[2,3-d] and thieno[3,2-d] pyrimidin-4-ones, dimethylformamide, dimethylaminomethyleneamino derivatives

Abstract

A simple and handy method for obtaining variable 3-N-substituted thieno[2,3-d] and thieno[3,2-d] pyrimidin-4-ones has been developed. The reaction of α- and β-amino ethyl thiophenecarboxilates with dimethylformamide dimethyl acetal forms the corresponding new dimethylaminomethyleneamino derivatives. Above mentioned derivatives when condensed with several aliphatic and aliphatic substituted primary amines form the targeted new 3-N-substituted thienopyrimidin-4-ones with high yields.

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Published

2011-11-08

Issue

Vol. 45 No. 3 (226) (2011)

Section

Chemistry

License

Copyright (c) 2011 Proceedings of the YSU

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

“A NEW APPROACH TO THE SYNTHESIS OF 3-N-SUBSTITUTED THIENOPYRIMIDINE-4-ONES ON THE BASE OF ETHYL AMINOTHIOPHENECARBOXILATES”. 2011. Proceedings of the YSU B: Chemical and Biological Sciences 45 (3 (226): 30-35. https://doi.org/10.46991/PYSUB.2011.45.3.030.