A NEW APPROACH TO THE SYNTHESIS OF 3-N-SUBSTITUTED THIENOPYRIMIDINE-4-ONES ON THE BASE OF ETHYL AMINOTHIOPHENECARBOXILATES
DOI:
https://doi.org/10.46991/PYSU:B/2011.45.3.030Keywords:
3-N-substituted thieno[2,3-d] and thieno[3,2-d] pyrimidin-4-ones, dimethylformamide, dimethylaminomethyleneamino derivativesAbstract
A simple and handy method for obtaining variable 3-N-substituted thieno[2,3-d] and thieno[3,2-d] pyrimidin-4-ones has been developed. The reaction of α- and β-amino ethyl thiophenecarboxilates with dimethylformamide dimethyl acetal forms the corresponding new dimethylaminomethyleneamino derivatives. Above mentioned derivatives when condensed with several aliphatic and aliphatic substituted primary amines form the targeted new 3-N-substituted thienopyrimidin-4-ones with high yields.
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Published
2011-11-08
How to Cite
Melikyan, G.S., A.A. Hovhannisyan, and L.A. Aristakesyan. 2011. “A NEW APPROACH TO THE SYNTHESIS OF 3-N-SUBSTITUTED THIENOPYRIMIDINE-4-ONES ON THE BASE OF ETHYL AMINOTHIOPHENECARBOXILATES”. Proceedings of the YSU B: Chemical and Biological Sciences 45 (3 (226):30-35. https://doi.org/10.46991/PYSU:B/2011.45.3.030.
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Chemistry
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