SYNTHESIS OF NEW 3-CYANOPYRIDINE-2(1H)-ONES WITH UNSATURATED SUBSTITUENTS AT C-4

Authors

  • A.A. Hovhannisyan Chair of Organic Chemistry, YSU, Armenia
  • L.H. Aristakesyan Chair of Organic Chemistry, YSU, Armenia
  • R.M. Hakobyan Chair of Organic Chemistry, YSU, Armenia
  • G.S. Melikyan Chair of Organic Chemistry, YSU, Armenia

DOI:

https://doi.org/10.46991/PYSU:B/2015.49.2.009

Keywords:

3-cyanopyridine-2(1H)-one, 2-oxo-1,2-dihydropyridine-3-carbonitrile unsaturated derivatives

Abstract

3-Cyanopyridine-2(1H)-ones containing unsaturated substituents at the position C-4 and various substituents at N-1 of the ring have been synthesized as new potential bioactive compounds by interaction of ethyl ylidene cyanoacetate with dimethylformamide dimethyl acetal, and simultaneous reamination-cyclization of obtained derivatives with amines to targeted 3-cyanopyridine-2(1H)-ones.

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Published

2015-07-10

How to Cite

Hovhannisyan, A.A., L.H. Aristakesyan, R.M. Hakobyan, and G.S. Melikyan. 2015. “SYNTHESIS OF NEW 3-CYANOPYRIDINE-2(1H)-ONES WITH UNSATURATED SUBSTITUENTS AT C-4”. Proceedings of the YSU B: Chemical and Biological Sciences 49 (2 (237):9-13. https://doi.org/10.46991/PYSU:B/2015.49.2.009.

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Section

Chemistry