ISOLATION, IDENTIFICATION AND QUANTITATIVE DETERMINATION OF NIFEDIPINE FROM BIOLOGICAL MATERIAL

Authors

  • Satenik Gh. Petrosyan Chair of Pharmaceutical Chemistry and Pharmacognosy, YSU, Armenia
  • Lusine Yu. Sahakyan Chair of Biomedicine, YSU, Armenia
  • Virab G. Kirakosyan Chair of Pharmaceutical Chemistry and Pharmacognosy, YSU, Armenia
  • Ella V. Minasyan Laboratory of Asymmetric Synthesis, Institute of Pharmacy, YSU, Armenia
  • Siranush Ye. Sardaryan Laboratory of Asymmetric Synthesis, Institute of Pharmacy, YSU, Armenia

DOI:

https://doi.org/10.46991/PYSU:B/2021.55.3.204

Keywords:

nifedipine, isolation, biological material and identification

Abstract

The optimal conditions of the method, applicable during forensic chemical examinations, were elaborated. Particularly, the investigation of the conditions for the isolation of Nifedipine from liver and skeletal muscle tissues, the identification of the isolated Nifedipine by TLC method and checking the accuracy of the method using HPLC was carried out. As a result, a new alternative express method for the isolation and further identification of Nifedipine from different biomaterials was elaborated. The method is quite fast, accurate and much cheaper.

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Published

2021-12-23

How to Cite

Petrosyan, Satenik Gh., Lusine Yu. Sahakyan, Virab G. Kirakosyan, Ella V. Minasyan, and Siranush Ye. Sardaryan. 2021. “ISOLATION, IDENTIFICATION AND QUANTITATIVE DETERMINATION OF NIFEDIPINE FROM BIOLOGICAL MATERIAL”. Proceedings of the YSU B: Chemical and Biological Sciences 55 (3 (256):204-11. https://doi.org/10.46991/PYSU:B/2021.55.3.204.

Issue

Vol. 55 No. 3 (256) (2021)

Section

Chemistry

License

Copyright (c) 2021 Proceedings of the YSU

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