EXTRACTION-PHOTOMETRIC DETERMINATION OF ANALGINUM BY FUCHSINE IN PHARMACEUTICALS
DOI:
https://doi.org/10.46991/PYSU:B/2009.43.3.054Keywords:
analginum, triphenilmethane, ionic associate, determination of analginumAbstract
Interaction of analginum anion with triphenilmethane (TPM) basic dye fuchsine has been studied. The colored ionic associate (IA) could be extracted by dichlorethane–acetone (2:1) binary mixture in pH 2 (H2SO4) solutions. The range of determined concentration of analginum is 7.11·10-5–1.423·10-3 M, of fuchsine is 4.44·10-4–1.04·10-3 M . A attitude of components in IA is 1:1. The elaborated method has been applied for determination of analginum in pentalgin-H, spasmalgonum, spasgan. In the case of tempalgin low results are received. Fuchsine is less sensitive, than earlier reported methods by other TPM dyes.
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