STUDY OF INTERACTION BETWEEN PURIFIED HYPERICIN PREPARATIONS AND DNA

Authors

  • A. R. Penesyan Chair of Biophysics, YSU, Armenia
  • A. P. Antonyan Chair of Biophysics, YSU, Armenia
  • H. R. Vardapetyan Chair of Biophysics, YSU, Armenia

DOI:

https://doi.org/10.46991/PYSU:B/2004.38.1.080

Keywords:

methanol extract, $Crocus~sativus$ L., gel-chromatography, hypericin

Abstract

Isolation and fractionation of total methanol extract, obtained from Hypericum perforatum L. flowers, using the method of gel-chromatography on columns, containing sephadex LH-20, were performed. Absorption and fluorescent spectroscopy, as well as the method of TLC have shown the high purity of obtained hypericin preparations. Interaction between hypericin and DNA was investigated. It was shown that hypericin interacts with purine and pyrimidine sequences of DNA selectively and in different ways.

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Published

2003-12-28

How to Cite

Penesyan, A. R., A. P. Antonyan, and H. R. Vardapetyan. 2003. “STUDY OF INTERACTION BETWEEN PURIFIED HYPERICIN PREPARATIONS AND DNA”. Proceedings of the YSU B: Chemical and Biological Sciences 38 (1 (203):80-85. https://doi.org/10.46991/PYSU:B/2004.38.1.080.

Issue

Vol. 38 No. 1 (203) (2004)

Section

Biology

License

Copyright (c) 2003 Proceedings of the YSU

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.