STUDY OF ASPIRIN EFFECT ON STABILITY OF MEMBRANES OF RAT BLOOD ERYTHROCYTES BY ACIDIC HEMOLYSIS METHOD

Authors

  • Marieta S. Mikaelyan Chair of Biophysics, YSU, Armenia
  • Mariam A. Shahinyan Chair of Biophysics, YSU, Armenia
  • Gayane H. Poghosyan Chair of Biophysics, YSU, Armenia
  • Evelina G. Sargsyan Scientific-research Laboratory of Biophysics of Subcellular Structures, Chair of Biophysics, YSU, Armenia
  • Anahit V. Nerkararyan Chair of Biophysics, YSU, Armenia

DOI:

https://doi.org/10.46991/PYSU:B/2022.56.1.056

Keywords:

erythrocyte membrane, acetylsalicylic acid, erythrocyte stability, hemolysis duration

Abstract

In this work the effect of aspirin on stability of rat blood erythrocyte membranes was studied, using acidic hemolysis method. Hemolysis rate of erythrocytes was shown to depend on preservation time of rat erythrocyte suspension. With increasing of preservation time the original value of optic density of rat erythrocyte suspension decreases and hemolysis time reduces. It was also shown that in the presence of aspirin the membrane stability of low-stable erythrocytes increases, moreover, hemolysis duration enhances, while aspirin leads to decreasing of membrane stability of both high-stable and enhanced-stable erythrocytes of rats.

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Published

2022-05-03

How to Cite

Mikaelyan, Marieta S., Mariam A. Shahinyan, Gayane H. Poghosyan, Evelina G. Sargsyan, and Anahit V. Nerkararyan. 2022. “STUDY OF ASPIRIN EFFECT ON STABILITY OF MEMBRANES OF RAT BLOOD ERYTHROCYTES BY ACIDIC HEMOLYSIS METHOD”. Proceedings of the YSU B: Chemical and Biological Sciences 56 (1 (257):56-62. https://doi.org/10.46991/PYSU:B/2022.56.1.056.

Issue

Vol. 56 No. 1 (257) (2022)

Section

Biology

License

Copyright (c) 2022 Proceedings of the YSU

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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