INVESTIGATION OF BIOLOGICALLY ACTIVE SUBSTANCES AND ANTIMICROBIAL ACTIVITY IN  STEVIA REBAUDIANA EXTRACTS

Authors

  • Melanya S. Ghazaryan Chair of Pharmaceutical Technology and Pharmacy Economics and Management, Institute of Pharmacy, YSU, Armenia
  • Tatevik H. Sargsyan Chair of Biomedical Sciences, Institute of Pharmacy, YSU, Armenia; Scientific and Production Center "Armbiotechnology" NAS RA, Armenia
  • Gohar F. Mkrtchyan Chair of Pharmaceutical Technology and Pharmacy Economics and Management, Institute of Pharmacy, YSU, Armenia
  • Svetlana H. Apoyan Chair of Pharmaceutical Technology and Pharmacy Economics and Management, Institute of Pharmacy, YSU, Armenia
  • Ani S. Dadayan Chair of Pharmtechnology and Pharmacy Economics and Management, Institute of Pharmacy, YSU, Armenia
  • Arpine V. Geolchanyan Institute of Pharmacy, YSU, Armenia
  • Samvel M. Vardapetyan Chair of Pharmaceutical Chemistry and Pharmacognosy, Institute of Pharmacy, YSU, Armenia
  • Khachik S. Hakobyan Chair of Biomedical Sciences, Institute of Pharmacy, YSU, Armenia
  • Anahit M. Hovhannisyan Chair of Pharmaceutical Technology and Pharmacy Economics and Management, Institute of Pharmacy, YSU, Armenia

DOI:

https://doi.org/10.46991/PYSUB.2025.59.1-2.012

Keywords:

diterpene glycosides, stevioside, HPLC method, stevia leaves

Abstract

The World Health Organization, taking into account available scientific studies, recognized Stevia (Sweet Clover) in 2006 as a harmless, beneficial crop and allowed its widespread use in food and pharmaceutical production. This decision has served as a basis for various scientific groups to continue large-scale studies on the composition and bioactivity of stevia. Considering the nearly complete absence of studies on the stevia cultivated in Armenia, this work investigates the quantitative content of certain biologically active substances in stevia grown in Armenia. The following data were obtained: diterpene glycosides 19.69%, fructose, glucose, and sucrose. The study of the antimicrobial properties of the water extract from the raw material showed that it possesses pronounced antimicrobial activity.

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Published

2025-06-30

Issue

Section

Chemistry

How to Cite

“INVESTIGATION OF BIOLOGICALLY ACTIVE SUBSTANCES AND ANTIMICROBIAL ACTIVITY IN  STEVIA REBAUDIANA EXTRACTS”. 2025. Proceedings of the YSU B: Chemical and Biological Sciences 59 (1-2 (266): 12-21. https://doi.org/10.46991/PYSUB.2025.59.1-2.012.

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